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MicroRNA 93

From Wikipedia, the free encyclopedia
MIR93
Identifiers
AliasesMIR93, MIRN9, MIRN93, hsa-mir-93, miR-93, microRNA 93
External IDsOMIM: 612984; GeneCards: MIR93; OMA:MIR93 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 7: 100.09 – 100.09 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

MicroRNA 93 is a functional RNA and a microRNA that in humans is encoded by the MIR93 gene. [3]

Function

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The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70 nucleotide long stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target messenger RNAs (mRNA) through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.[4]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000207757Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: MicroRNA 93". Retrieved 2018-10-24.
  4. ^ RefSeq, Sep 2009

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.